WebAug 8, 2024 · Cotreatment with chloroquine (10 μM) partially restored cell viability. The study showed that zinc deficiency induces autophagy and may be cytoprotective in neurons. We expect our results to add a new perspective to our understanding of the neuronal pathology related to zinc deficiency. ... A study in yeast showed that zinc deficiency … WebFeb 7, 2024 · Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South …
Sensitivity of yeast glycolytic enzymes to chloroquine
WebChloroquine at pH 8.0 and 10 mM concentration inhibits about 30% glucose consumption and ethanol formation in yeast cells. Out of the 11 glycolytic enzymes assayed, … WebOct 26, 2024 · Treatment with chloroquine or monensin was found to induce an LAP-like process of direct LC3 recruitment to the intact single phagosomal membrane, without ubiquitination, PI3P production, or WIPI involvement, and independent of ATG13 and of the FIP200-binding domain of ATG16L1. isles of siptah map
Chloroquine inhibits autophagic flux by decreasing …
WebJul 1, 1988 · Abstract. Chloroquine at pH 8.0 and 10 mM concentration inhibits about 30% glucose consumption and ethanol formation in yeast cells. Out of the 11 glycolytic enzymes assayed, phosphoglycerate kinase and pyruvate decarboxylase have been found to be most sensitive to chloroquine. WebSep 26, 2012 · Strikingly, these sensors indicated that chloroquine is a potent pro-mitochondrial drug which stimulated yeast sexual reproduction. In addition, these … WebApr 7, 2024 · The COVID-19 pandemic caused by SARS-CoV-2 has resulted in an urgent need for identifying potential therapeutic drugs. In the first half of 2024 tropic antimalarial drugs, such as chloroquine (CQ) or hydroxochloroquine (HCQ) were the focus of tremendous public attention. In the initial periods of the pandemic, many scientific results … kgf chapter 2 hindi torrent