Cisplatin induced cardiotoxicity
WebCardioprotective effect of zingerone against oxidative stress, inflammation, and apoptosis induced by cisplatin or gamma radiation in rats Despite their clinical benefits in cancer treatment, the deleterious effects on heart following chemo/radiotherapy are of increasing importance. WebFeb 2, 2024 · 5.1 Cisplatin-Induced Nephrotoxicity. Cisplatin, a potent chemotherapeutic agent used for treating various types of solid organ tumors, is limited by its serious side effects in clinical application (Yu et al., 2024; Deng et al., 2024). Cisplatin can cause an increase in the expression of NF-κB and TNF-α in the liver and kidney (Park et al., 2024
Cisplatin induced cardiotoxicity
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WebDrug-induced cardiotoxicity limits or forbids further use of the implicated drugs. Such drugs that are currently available in the clinic include anti-tumor drugs (doxorubicin, cisplatin, trastuzumab, etc.), antidiabetic drugs (rosiglitazone and pioglitazone), and an antiviral drug (zidovudine). WebLung cancer is a malignant tumor characterized by a rapid proliferation rate, less survivability, high mortality, and metastatic potential. This review focuses on updated research about the clinical application of traditional Chinese medicine (TCM) as an adjuvant therapy to lung cancer treatment and the mechanisms of TCM effect on lung cancer in …
WebThe current study aimed to investigate the curative role of semaglutide's against cisplatin- induced cardiotoxicity and its relation to mitochondrial functions, dynamics, biogenesis, apoptosis, and redox status pathways. The study included 30 male rats divided into three groups: control, cisplatin-induced cardiotoxicity, and cisplatin-induced ... WebMay 9, 2024 · Busulfan-induced pulmonary injury; Cardiotoxicity of cancer chemotherapy agents other than anthracyclines, HER2-targeted agents, and fluoropyrimidines ... et al. …
WebOct 1, 2010 · The increase in MDA may be due to the formation of oxygen-free radicals during cisplatin-induced cardiotoxicity, which react with membrane lipids, proteins, and nucleic acids and can cause ... WebApr 14, 2024 · While the exact mechanisms underlying the relationship between gut microbiota and chemotherapy-induced cardiotoxicity are not yet fully understood, …
WebFeb 21, 2024 · Cardiotoxicity of trastuzumab and other HER2-targeted agents; Cisplatin nephrotoxicity; Clinical manifestations, diagnosis, and treatment of anthracycline-induced cardiotoxicity; Drug-induced thrombotic microangiopathy (DITMA) Endocrine therapy …
WebJun 1, 2013 · At present, no data is provided explaining the mechanism of NO in cisplatin-induced cardiotoxicity. It has been found that NO and its metabolites, including … creative dance and music harveyWebApr 15, 2024 · Cisplatin is mostly used in combination with other chemotherapy drugs to overcome drug-resistance and reduce toxicity [reviewed in ( 95 )]. Cisplatin-based chemotherapy has been reported to cause cardiovascular diseases, particularly myocardial infarction and angina, in a range of 7–32% of patients ( 96) [reviewed in ( 97 )]. creative design agency manchesterWebMar 21, 2024 · However, HES protection against cisplatin (CP)-induced cardiotoxicity and its mechanism have not been fully clarified. The current study was performed to … creative dance belchertownWebCancer therapy can result in cardiac toxicity, such as cardiomyopathy. Cardiotoxicity with chemotherapeutic agents in the form of cardiomyopathy was first described in 1966 in patients receiving anthracyclines. 1 However, cancer treatment–induced arrhythmia (CTIA) has not attracted specific attention until recently. 2. creative data systems incWebHowever, it has a wide variety of side effects such as hepato, gastrointestinal, neuro, nephro, and cardiotoxicity (acute and/or chronic) th … The efficiency of blackberry loaded AgNPs, AuNPs and Ag@AuNPs mediated pectin in the treatment of cisplatin-induced cardiotoxicity in experimental rats creative description of an islandWebJan 10, 2011 · Cisplatin-induced cardiotoxicity Acetyl-l-carnitine DL-α-lipoic acid Silymarin Mitochondrial DNA Apoptosis 1. Introduction Cisplatin is one of the most remarkable successes in ‘the war on cancer’. Since the accidental discovery four decades ago, cisplatin has been widely used for chemotherapy. creative d200 wireless speakerWebApr 4, 2024 · Hesperidin (HES) is an abundant and economical dietary bioflavonoid, and it has several pharmacological properties such as antioxidant activity and powerful cardiac protection. However, HES protection against cisplatin (CP)-induced cardiotoxicity and its mechanism have not been fully clarified. creative cuts brunswick ohio