WebAug 8, 2024 · Historically, triple-class RRMM, defined as a disease that is refractory to a proteasome inhibitor, an immunomodulatory drug and an anti-CD38 antibody, portends a poor prognosis with overall ... WebJun 28, 2024 · Relapsed refractory multiple myeloma (RRMM) refers to multiple myeloma that is particularly difficult to treat. Multiple myeloma is relatively rare and only represents …
What to know about relapsed refractory multiple myeloma
WebFeb 24, 2024 · Understanding Relapsed/Refractory Multiple Myeloma (RRMM) Myeloma, also known as multiple myeloma, is a rare type of cancer arising from plasma cells that are normally found in the bone marrow. 2 Plasma cells are a type of white blood cell that forms part of the immune system. Myeloma affects multiple places in the body (hence the term ... WebAug 30, 2024 · Once anti-CD38 agents became widely available the clinical nature and history of patients with RRMM changed and the old definition of RRMM was no longer appropriate. This resulted in two new functional definitions, which are currently still in use: triple class-exposed (prior IMiD, PI, and anti-CD38 antibody) and penta-refractory (prior ... scituate football
Management of multiple myeloma in the relapsed/refractory patient
WebJul 31, 2024 · Abstract and Figures. The therapeutic strategy for relapsed and refractory multiple myeloma (RRMM) integrates a holistic approach regarding patient, disease, and drug-related factors. Patient ... WebOct 14, 2024 · Functionally, the development of RRMM is based on changes of the intrinsic tumor cell biology (e.g., evolving genomic sub/clonal aberrations; evolving mechanisms of resistance against initial therapies; deregulated signaling pathways; deregulated … WebApr 21, 2024 · Over the past decade, several drugs have been approved for the treatment of relapsed or refractory multiple myeloma (RRMM). This retrospective study, using the … prayer points for divine intervention