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Dek c terminal domain containing protein

WebThe START domain is always located in the C-terminus of the protein. It is a module of about 210 residues that binds lipids, including sterols. Cholesterol, 25-hydroxycholesterol, phosphatidylcholine, phosphatidylethanolamine and ceramides are ligands for STARD1/STARD3-6, STARD5, STARD2/STARD10, STARD10 and STARD11, … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules)

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Webacidic domain containing protein DEK might have a role in modulating both transcriptional regulation and apoptosis through HAT inhibitory activity. ... phosphorylated DEK is … WebAug 1, 2004 · We also found two DNA binding domains of DEK, one on a fragment including amino acids 87 to 187 and containing the SAF-box DNA binding motif, which is located between amino acids 149 and 187. installation security office https://cathleennaughtonassoc.com

Pfam: Family: DEK_C (PF08766)

WebDec 8, 2004 · The protein DEK is an abundant and ubiquitous chromatin protein in multicellular organisms (not in yeast). ... SSH1 also contains a DEK-C domain in the N-terminal region. The N-terminal fragment of SSH1 bound to and co-localized with F-actin, but mutation at Arg-96 or a Leu-His-Lys (LHK) motif in the PH-like domain reduced this … WebSolution NMR structure of the N-terminal domain of the human DEK protein Protein Sci. 2008 Feb;17(2):205-15. doi: 10.1110/ps.073244108. ... We found that not only the C … Web112-267: 3.33e-104: RUN domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins; RUFY1, also called FYVE-finger protein EIP1, or La-binding protein 1 jewish phonebook online

PDB 1q1v citation summary ‹ Protein Data Bank in Europe (PDBe) …

Category:CDD Conserved Protein Domain Family: DEK_C - National …

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Dek c terminal domain containing protein

UniProt

WebApr 1, 2005 · The 375-residue human protein DEK is a proto-oncogene protein that is associated with chromatin [1]. DEK was first discovered in patients with a subtype of acute myelogenous leukemia (AML) as a fusion product in which its C-terminal 26 amino acids are replaced by the N-terminal two-thirds of the nucleoporin CAN [2].

Dek c terminal domain containing protein

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WebThe C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH). When the protein is translated from messenger RNA, it is created from N-terminus to C-terminus. The convention for … WebJul 6, 2004 · The structure of the C-terminal region of DEK provides insights into the protein function of DEK. Keywords: NMR structure, oncogene product, ataxia-telangiectasia, acute myeloid leukemia, chromatin-associated protein, chromosomal translocation The 375-residue DEK protein is abundant in the nucleus and is associated …

WebThe SCOP classification for the DEK C-terminal domain superfamily including the families contained in it. Additional information provided includes InterPro annotation (if available), … WebJan 2, 2009 · For DNA binding experiments, amino acids 68–194 from human DEK were ligated into the bacterial expression vector pET30a (Novagen) as a fusion protein with …

WebDEK C-terminal domain-containing protein InterPro annotation. Gene names. Name. 100812080 Imported. ORF names. GLYMA_08G329200 Imported. Organism names. … WebFeb 1, 2008 · The 375-residue, 45 kDa DEK protein was first identified in patients with a subtype of AML as a fusion product in which its C-terminal 26 amino acids are replaced by the C-terminal two-thirds of the nucleoporin CAN (von Lindern et al. 1992).Overexpression of DEK has been found in a number of aggressive human tumors including acute …

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules)

Webconserved DEK domain-containing protein is implicated in important chromatin-related processes in animals, but little is known about its DNA targets and protein interaction … jewish phone book williamsburgWebFeb 1, 2016 · The DEK_C domain is related to the C-terminal of animal DEK protein, which is responsible for self-multimerization and DNA binding ( Kappes et al., 2004 ). Nevertheless, the role of the DEK_C domain in … jewish phone directory brooklynWebJan 2, 2009 · The C-terminal region of DEK has a three helix bundle structure similar to that of winged-helix DNA-binding proteins such as DP2 (Devany et al. 2004 ). In this report, we describe the three-dimensional structure of the N-terminal region of DEK and its dsDNA-binding properties. Figure Figure 1. Open in figure viewer PowerPoint jewish philosopher spinoza