WebOct 5, 2024 · In total, 930 patients were randomized to therapeutic hypothermia and 931 to normothermia. The hypothermia group had mortality of 50% while the normothermia group had mortality of 48% (relative risk [RR] 1.04, 95% confidence interval [CI] 0.94–1.14). The proportion of patients with mRS of 4 to 6 was 55% in both groups (RR 1.00, 95% CI … WebJul 3, 2024 · Reference: Dankiewicz et al: TTM2 Trial Investigators.Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest. NEJM 2024. Population: Comatose adult patients admitted to hospital after an OHCA, irrespective of initial rhythm. Intervention: Hypothermia with a target temperature of 33 degrees Celsius, maintained for 28 hours, …
Hypothermia vs. Normothermia after OHCA Key Article Dankiewicz …
WebJan 29, 2024 · @article{Shrestha2024HypothermiaVN, title={Hypothermia versus normothermia after out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized controlled trials}, author={Dhan Bahadur Shrestha and Yub Raj Sedhai and Pravash Budhathoki and Suman Gaire and Anurag Adhikari and Ayusha Poudel and … WebJul 22, 2024 · The authors of the TTM trial have now come out with their subsequent study looking to assess the benefit of avoiding fever versus targeting a specific temperature in critically ill patients following cardiac arrest. Paper: Dankiewicz J et al. Hypothermia Versus Normothermia After Out-Of-Hospital Cardiac Arrest. NEJM 2024. PMID: 34133859 raid 0 also known as
Does hypothermia versus normothermia after out-of-hospital …
WebJun 17, 2024 · In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not lead to a lower incidence of death by 6 months than targeted normothermia. (Funded by the Swedish Research Council and others; TTM2 ClinicalTrials.gov number, NCT02908308.). WebJun 17, 2024 · At 6 months, 465 of 925 patients (50%) in the hypothermia group had died, as compared with 446 of 925 (48%) in the normothermia group (relative risk with hypothermia, 1.04; 95% confidence interval [CI], 0.94-1.14; p = 0.37). Of the 1,747 patients in whom the functional outcome was assessed, 488 of 881 (55%) in the hypothermia … WebNov 9, 2024 · TTM at 33°C vs. normothermia 37.5°C : Survival with a CPC of 1 or 2 at 90 days: Significantly improved survival with a CPC of 1 or 2 in hypothermia group but no difference in overall mortality: Dankiewicz et al. [TTM2 trial] 1861: RCT: 2024: OHCA with a presumed cardiac cause: TTM at 33°C vs. targeted normothermia 37.5°C : Death from … raiculopathy \\u0026pain in neck