2024 Otoferlin abcam

Otoferlin abcam

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August undefined, 2024

WebNov 7, 2016 · Otoferlin first appeared in 1999, when it was discovered that mutations of the OTOF gene cause a nonsyndromic form of deafness (Yasunaga et al, 1999).These … WebAbcam mouse otoferlin Mouse Otoferlin, supplied by Abcam, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article …

Otoferlin, Defective in a Human Deafness Form, Is Essential for ...

WebProvided herein are compositions that include at least two different nucleic acid vectors, where each of the at least two different vectors includes a coding sequence that encodes … WebAnti-Otoferlin Antibody Products from Abcam. Anti-Otoferlin antibodies are available from several suppliers. In humans, this protein is encoded by the gene OTOF. The protein may … mourning cast

Otoferlin Depletion Results in Abnormal Synaptic Ribbons and …

WebOct 4, 2010 · Subsequent immunoblots against otoferlin used a monoclonal anti-otoferlin provided by S. Safieddine (Université Pierre et Marie Curie, Paris, France). For otoferlin … WebJun 20, 2010 · We propose that otoferlin is involved in replenishing ... mouse antibody to calbindin (Swant, 1:500), mouse antibody to otoferlin (N terminal, Abcam, 1:500), rabbit … WebMar 21, 2024 · OTOF (Otoferlin) is a Protein Coding gene. Diseases associated with OTOF include Deafness, Autosomal Recessive 9 and Otof-Related Deafness.Among its related … mourning christ

Article Function coupling of otoferlin with GAD65 acts to modulate

Truncation of the otoferlin transmembrane domain alters the …

WebMar 30, 2011 · Cochlear inner hair cells (IHCs) use Ca2+-dependent exocytosis of glutamate to signal sound information. Otoferlin (Otof), a C2 domain protein essential for IHC … WebFeb 20, 2015 · Otoferlin is essential for a late step of exocytosis including vesicle priming and fusion ... and anti-otoferlin (1:200, Abcam ab53233). After 3 × 10 min washes in PBS … heart projectionWebOct 3, 2024 · The protein otoferlin plays an essential role at the sensory hair cell synapse. Mutations in otoferlin result in deafness and depending on the species, mild to strong … mourning chart

"WebAbcam - antibodies and reagents supplier, find any antibody Hello. We're improving abcam.com and we'd welcome your ... Mouse monoclonal [13A9] to Otoferlin. Application: … " - Otoferlin abcam

Otoferlin abcam

Anti-Otoferlin antibody [13A9] Abcam ab53233 product information

WebApr 13, 2024 · The OTOF gene encodes otoferlin, a protein that enables the inner hair cells of the cochlea to release neurotransmitter vesicles in response to stimulation by sound to … Web上海易汇生物科技有限公司，是一家集研发、销售为一体的高新技术生物企业，公司专注于生命科学和生物技术领域，专业提供分子生物学、免疫学、生命科学基础研究以及临床检测 …

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WebMay 29, 2013 · Otoferlin, a transmembrane protein responsible for deafness in DFNB9 families, has been postulated to act as a calcium sensor for ... Santa Cruz Biotechnology), … WebDec 27, 2024 · Anti-Otoferlin antibody [13A9] Abcam catalog: ab53233. mouse monoclonal (13A9) ... All lanes: Anti Otoferlin (PB9616) at 0.5ug/ml. Lane 1: Rat Cardiac Muscle …

WebThe disclosure provides Sox2 inhibitors that can be used to generate Type I vestibular hair cells in the vestibular system. The Sox2 inhibitors may be administered to a subject alone or in combination with a regeneration agent to convert Type II vestibular hair cells or regenerated vestibular hair cells to Type I vestibular hair cells. WebJul 10, 2024 · Sensory hair cells rely on otoferlin as the calcium sensor for exocytosis and encoding of sound preferentially over the ... were equilibrated in PBS, pH 7.5, and conjugated to 1 μg of anti-GFP antibody …

WebNov 14, 2015 · Overlapping with otoferlin, each F-actin cage was generally associated with one ribbon and one ... anti-Cav1.3 (Rabbit polyclonal, Alomone labs, Jerusalem, Israel; cat …

WebAug 11, 2024 · The OTOF gene encodes otoferlin, a protein that enables the inner hair cells of the cochlea to release neurotransmitter vesicles in response to stimulation by sound to activate auditory neurons. Most individuals with OTOF -mediated hearing loss have Severe to Profound sensorineural hearing loss from birth and approximately 20,000 individuals are …

WebAug 22, 2024 · In mammal myocytes, endothelial cells and inner ear cells, ferlins are proteins involved in membrane processes such as fusion, recycling, endo- and exocytosis. They harbour several C2 domains allowing their interaction with phospholipids. The expression of several Ferlin genes was described as altered in several tumoural tissues. Intriguingly, … heart projectorWebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that … heart projector lightWebDAPI is a dye for staining nuclei, N-terminal and C-terminal otoferlin are immunostained by antibodies of anti N-terminal and C-terminal otoferlin (ab53233, Abcam; PA552935, … mourning chorusWebOct 17, 2006 · A form of sensorineural hearing loss with absent or severely abnormal auditory brainstem response, in the presence of normal cochlear outer hair cell function … mourning-cloakWebNov 16, 2024 · DAPI is a dye for staining nuclei, N-terminal and C-terminal otoferlin are immunostained by antibodies of anti N-terminal and C-terminal otoferlin (ab53233, … mourning cloak butterfly habitatWebNov 26, 2024 · synaptic vesicles. Together with the ﬁnding of otoferlin immunoreactivity on endosomal vesicular structures, it was concluded that otoferlin is involved in the reformation of synaptic vesicles from bulk endosomes [13]. This is in agreement with the ﬁnding that otoferlin interacts with the clathrin adaptor protein AP2 [15,16]. heart project xlWebNov 7, 2016 · otoferlin and shows that this is mediated via the tail-anchored protein insertion pathway TRC40 (Vogl et al, 2016). The primary otoferlin defect in hearing-impaired … mourning cards templates