The hub genes
WebMar 23, 2024 · Hub genes were verified in patients using quantitative real-time polymerase chain reaction (qRT-PCR). Results We identified 3,132 DEGs in blood samples and 253 DEGs in left atrial specimens. Co-expressed hub genes of EIF4E3, ZNF595, ZNF700, MATR3, ACKR4, ANXA3, SEPSECS-AS1, and RNF166 were significantly associated with AF-related …
The hub genes
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WebThe purpose of this study was to identify hub genes closely correlated with Alzheimer's disease (AD) and their association with immune cell infiltration. In this work, 119 overlapping differentially expressed genes (DEGs) were obtained from GSE5281 and GSE122063 datasets through differential expression analysis. Gene Ontology (GO) and Kyoto … Webtic strategy in RA due to a lack of systematic studies on validated biomarkers. The present study aimed to identify hub pyroptosis biomarkers and immune infiltration in RA. The gene expression profiles of synovial tissues were obtained from the Gene Expression Omnibus (GEO) database to identify differentially expressed pyroptosis genes (DEPGs). Meanwhile, …
WebAug 20, 2024 · Finally, 30 hub genes were identified in three modules. Hub genes with a high degree of connectivity in the PPI network are significantly enriched in positive regulation of transcription. In addition, the hub genes were validated based … WebJul 23, 2024 · Hub genes are a class of highly connected genes within a module and are significantly associated with biological function [ 18 ]. In this study, we defined genes with high module membership (MM) ( cor.weighted > 0.8) as hub genes. We considered hub genes present in both GSE45216–98774 and GSE108008 as validated hub genes.
WebJan 27, 2024 · The RNASEL, MAPK4, SPI1, MYBL2, and MYBL1 genes were determined as hubs in the BP vs. AP network. In the P vs. AP network, the HSPA8, ND5, ABCA2, GATA1, and CYTB genes were the top five hub... WebOct 17, 2024 · Hub genes in each co-expressed module were defined according to module eigengene-based intramodular connectivity or module membership (kME) index in non-preserved modules ( Panahi and Hejazi, 2024 ). Genes with kME ≥ 0.7 were considered as hub genes in the respective module ( Langfelder and Horvath, 2008 ).
WebThen we applied CytoHubba to calculate the degree of each protein node. The results demonstrated that the top 10 genes ranked by the node degree were IL6, MMP3, INHBA, …
WebApr 12, 2024 · We built a network of PPI using String, after which hub genes were identified using Cytohubba and MCODE. Cytohubba determined the top 10 genes based on node … fnf bambi\\u0027s hellscape onlineWebMay 20, 2024 · Despite the genes and pathways associated with NP development we found, 8 hub genes (C3, C1qb, Ccl2, Cxcl13, Timp1, Fcgr2b, Gal, Lyz2) that were responsible for NP development regulation were identified and some of them have been reported to present an intimate correlation with NP development. fnf bambi\\u0027s hellscape 2.0WebMay 3, 2024 · Background Recent evidences indicated that shear stress is critical in orchestrating gene expression in cardiovascular disease. It is necessary to identify the mechanism of shear stress influencing gene expression in physiology and pathophysiology conditions. This paper aimed to identify candidate hub genes and its transcription factors … fnf bambi\\u0027s hellscape v2WebOf the 4 hub genes significantly correlated with OS in AML, SUSD3 is a cell-surface protein with unknown function that may be involved in the growth and development of breast cancer via the estrogen receptor pathway. Some evidence indicates that the gene acts downstream of the estrogen receptor and that estrogen enhances its expression. green tonys chocolateWebApr 6, 2024 · Thus, these hub genes associated with immune cells could serve as potential therapeutic targets for AMI treatment. Moreover, our results (Figure 10) showed a synergistic effect between activated NK cells and Tregs cells as well as a competitive effect between gamma delta T cells and neutrophils. A few studies have reported the relationship. green toolbox foamWebJul 2, 2024 · According to the method of maximal clique centrality (MCC), the top 10 hub genes included secreted phosphoprotein 1 (SPP1), vascular endothelial growth factor A … green tool boxes for saleWebApr 12, 2024 · AMA Style. Zhu J, Min N, Gong W, Chen Y, Li X. Identification of Hub Genes and Biological Mechanisms Associated with Non-Alcoholic Fatty Liver Disease and Triple-Negative Breast Cancer. green tony lama boots