WebPVDF membrane was probed with 1 µg/mL of Mouse Anti-Human TRF2 Monoclonal Antibody (Catalog # MAB5635) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). A specific band was detected for TRF2 at approximately 75 kDa (as indicated). This experiment was conducted under reducing conditions and using … WebAn important telomere binding protein, TTAGGG repeat factor 2 (TRF2), is thought to protect telomere ends by remodeling them into T-loops. We show that TRF2 specifically interacts with telomeric ss/ds DNA junctions and binding is sensitive to the sequence of the 3′, guanine-strand (G-strand) overhang and double-stranded DNA sequence at the ...
Anti-TRF2 Antibody, clone 4A794 - Sigma-Aldrich
WebA large number of proteins involved in the DNA damage response are found physically associated with TRF2 within telomeres (3). Interestingly, TRF2 can transiently localize to DNA damage-induced DSBs, but overexpression of TRF2 prevents ATM-dependent … WebAnti-TRF2 Antibody, clone 4A794 is a Mouse Monoclonal Antibody for detection of TRF2 also known as Telomeric repeat-binding factor 1 & has been tested in ICC & WB. Research … surya golds pvt. ltd
TRF-2 Antibody (4A794.15) - BSA Free - Novus Biologicals
WebThe TRF2 antibody is referred to as both clone 4A794.15 and 4A794 in the published literature. This antibody recognizes full-length TRF2 as well as TRF2 forms lacking both the N-terminal basic domain (B) and the telobox Myb-like C-terminal DNA-binding domain (M). WebChIP-seq (chromatin immunoprecipitation [ChIP] combined with deep sequencing) analysis of Drosophila embryos using anti-TRF2 antibodies indicate a peak of TRF2 occupancy in the vicinity of the TSS. We analyzed this ChIP-seq data set and discovered that, remarkably, the most enriched motif in the top TRF2-bound genes (quantile 0.9) is the ... WebMar 15, 2009 · Successfully established an antibody-drug conjugate program and supported biomarker discovery and development of small molecule and ... Six core proteins-TRF1, TRF2, TIN2, POT1, TPP1 and ... surya inversiones